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cit | Article | May/June 2024

Key Questions for Ongoing and Future Renal Denervation Trials

Dr. Ajay J. Kirtane discusses where renal denervation devices fit in the blood pressure control landscape, remaining questions to be addressed, ensuring patient access to this therapeutic option, and ideal goals for future trials.

cit | Article | September 2008

Clinical Trial Update on the Endeavor Stent

An overview of the completed and ongoing clinical trial program of the Endeavor zotarolimus-eluting stent platform.

By Ajay J. Kirtane, MD, SM; Marcos Valerio, BS; and Martin B. Leon, MD

cit | Article | May/June 2025

Next Frontiers in HTN Denervation

Reflections on the next generation of RDN trials and their potential endpoints, how to handle data collection, and new applications beyond renal.

With Felix Mahfoud, MD, MA; Ajay J. Kirtane, MD; and Andrew Sharp, MD

cit | Article | September/October 2024

Radiation Protection in Structural Heart Disease Procedures: Strategies to Reduce Exposure

A review of newer radiation protection technologies and efforts to reduce radiation exposure to the operator and interventional echocardiographer.

By Poonam Velagapudi, MD, MS; Lucy M. Safi, DO; Ajay J. Kirtane, MD, SM; and James Hermiller, MD

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Sponsored by Boston Scientific Corporation

cit | Article | May/June 2015

Renal Denervation: What Is on the Horizon?

A look at the background of renal denervation studies and the future directions of this therapy for patients with hypertension.

With Krishna Rocha-Singh, MD; Farrell O. Mendelsohn, MD; and Ajay J. Kirtane, MD, SM, FACC, FSCAI

cit | Article | January/February 2018

Insights Into the FAME 2 and ORBITA Trials

Drs. William Fearon and Ajay Kirtane discuss what the data mean for patients with stable coronary artery disease undergoing percutaneous coronary intervention, applicability in patients with severe disease, and what they would have changed in terms of study design.

With William Fearon, MD, and Ajay J. Kirtane, MD, SM, FACC, FSCAI

cit | Article | September/October 2023

Renal Denervation: Where We Stand After the FDA Panels

Experts’ thoughts on what defines a clinically meaningful reduction in blood pressure, roles of office-based and ambulatory blood pressure monitoring, ideal candidates for renal denervation and patient preference as a driver for the procedure, options that could meet the FDA's request for more data, and applying a team-based approach to screening and treatment.

With Ajay J. Kirtane, MD, SM; Eric A. Secemsky, MD, MSc, RPVI, FACC, FSCAI, FSVM; and Taisei Kobayashi, MD

cit | News | September 25, 2019

EVOLVE Short DAPT Study Shows Low Rate of Adverse Events in High-Bleeding Risk Patients

September 26, 2019—The Cardiovascular Research Foundation (CRF) announced that results from the EVOLVE Short DAPT study were presented by lead investigator Ajay J. Kirtane, MD, at TCT 2019, the 31st annual Transcatheter Cardiovascular Therapeutics scientific symposium, which is sponsored by CRF and held September 25–29 in San Francisco, California.

cit | News | March 1, 2021

Primary Results of the EVOLVE Short DAPT Study Are Published

March 1, 2021—Findings were published from the EVOLVE Short DAPT trial, which prospectively evaluated the safety of 3-month dual antiplatelet therapy (DAPT) in patients at high bleeding risk treated with the Synergy everolimus-eluting stent (Boston Scientific Corporation).

cit | News | November 17, 2025

Neurotronic’s Neuviant Multiorgan Denervation Studied to Treat Type 2 Diabetes and Hypertension 

November 17, 2025—Neurotronic, Inc. announced the first clinical outcomes of the NECTAR III and NECTAR IV trials evaluating the company’s Neuviant multiorgan denervation (MDN) system in patients with both type 2 diabetes mellitus (T2DM) and hypertension (HTN).

cit | News | May 19, 2025

Cordis Initiates SELUTION Global Coronary Registry

May 19, 2025—Cordis announced the initiation of the SELUTION Global Coronary Registry.

cit | News | November 15, 2023

Recor Medical’s Paradise uRDN System Launched in United States

November 14, 2023—Recor Medical, Inc. and its parent company, Otsuka Medical Devices Co., Ltd., have announced the first commercial uses of Recor’s Paradise ultrasound renal denervation (uRDN) system for the treatment of hypertension.

cit | News | April 3, 2026

ALL-RISE Compares CathWorks’ FFRangio to Invasive Pressure Wire Guidance

April 3, 2026—CathWorks announced 1-year clinical outcomes of the ALL-RISE trial.

cit | News | January 6, 2025

CathWorks FFRangio System’s ALL-RISE Trial Completes Enrollment

January 6, 2025—CathWorks recently announced the completion of enrollment for the ALL-RISE randomized controlled trial, evaluating the clinical and economic benefits of the CathWorks FFRangio system in diagnosing and treating coronary artery disease.

cit | News | April 19, 2024

MAGICAL-ISR IDE Study of Concept Medical’s MagicTouch Sirolimus DCB Begins Enrollment

April 19, 2024—Concept Medical announced the commencement of the MAGICAL-ISR investigational device exemption (IDE) clinical study.

cit | News | June 28, 2021

Shockwave Medical’s Intravascular Lithotripsy System Evaluated in Three Published Studies

June 28, 2021—Shockwave Medical, Inc. announced the publication of evaluations of the safety, efficacy, and mechanism of the benefit of the company’s intravascular lithotripsy (IVL) for the treatment of coronary and peripheral artery disease (PAD).

cit | News | December 10, 2020

ReCor Medical’s Paradise Renal Denervation System Receives FDA Breakthrough Device Designation

December 10, 2020—ReCor Medical, Inc., a wholly owned subsidiary of Otsuka Medical Devices, announced that its catheter-based Paradise ultrasound renal denervation system has received FDA Breakthrough Device designation for the treatment of patients with uncontrolled hypertension who are not sufficiently responsive, or are intolerant, to antihypertensive medical therapy.

cit | Article | May/June 2024

Technical Essentials

By Andrea Scotti, MD, and Azeem Latib, MD

cit | News | April 16, 2013

Accumetrics Obtains CE Mark for Therapeutic Window Claim on the VerifyNow P2Y12 Test

April 16, 2013–Accumetrics, Inc. (San Diego, CA) announced an expansion in the intended use for the company's CE Mark-approved VerifyNow P2Y12 test.

cit | News | June 28, 2023

First Patient Enrolled in CathWorks ALL-RISE Study Evaluating FFRangio System

June 28, 2023—CathWorks announced that the first patient has been enrolled in the ALL-RISE study sponsored by the company.


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Coding CTO DES Hypertension Imaging Modalities PCI Pharmacology Radial Regulatory Structural Disease Valvular Interventions
Centers

Coding CTO DES Hypertension Imaging Modalities PCI Pharmacology Radial Regulatory Structural Disease Valvular Interventions

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Cardiac Interventions Today (ISSN 2572-5955 print and ISSN 2572-5963 online) is a publication dedicated to providing coverage of the latest developments in technology, techniques, clinical studies, and regulatory and reimbursement issues in the field of coronary and cardiac interventions.



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