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September/October 2010
An Interview with Ramon Quesada, MD
From transradial access to percutaneous mitral valve repair, Dr.Quesada gives us a personal look at the interventional cardiology field.
Do you think that as the transradial access approach
gains prevalence in the United States, medical schools
and fellowship programs will incorporate this technique?
One of the reasons that operators in the United States have not yet adopted this technique is that they are more comfortable with femoral access, and there is a learning curve associated with this new method. I saw the first transradial procedure around 1996, and I really jumped on the technique and was committed to mastering it. So, although it takes time to learn this technique, once the operator is comfortable using this access approach, applying it to varying subsets of cases is not problematic—you are going to the same place, just using a different direction.
In your opinion, where can interventionists find the
best training programs to learn or better hone their
transradial access skills?
There are very few hands-on training programs in the
United States that I know of, but the training process can be
didactic. Most interventionists who have adopted the transradial
approach are advanced operators, so switching from
femoral to transradial access is a commitment more than
anything else. It would be great if there was access to handson
training programs, but honestly, I do not believe that
they are necessary. This is a technique that can be adopted based on didactic courses that you can learn in a few steps
using the basic tools, as long as you are committed to going
through the associated learning curve.
Are you currently participating in any clinical trials?
Apart from my coronary work, I do a significant amount
of structural work. At Baptist Cardiac & Vascular Institute, I
have participated in a patent foramen ovale closure trial,
which was completed and will be presented at the
American Heart Association meeting in
November. Currently, we are involved in
two percutaneous mitral valve repair trials
studying the MitraClip device (Abbott
Vascular, Santa Clara, CA): the EVEREST trial
and the current REALISM registry. I am also
participating in left atrial appendage closure
trials with the Watchman device (Atritech,
Inc., Plymouth, MN), which include the initial
PROTECT study, as well as the CAP registry.
Additionally, we will be involved in the
next phase of the PREVAIL study, which is a
randomized trial that will begin shortly. Of
course, we are eager to take on new protocols and devices.
Can you share a preview of some of the areas that ISET
2011 will focus on? Are there any new features or topics
that you are excited about?
As a matter of fact, in the peripheral arena, there is going
to be a lot of emphasis on the new forms of therapy, which
is fascinating to me even though I don't perform peripheral
interventions. In the vascular field, forms of therapy for multiple
sclerosis will be one of the new features. In the cardiac
arena, of course there will be a focus on complex coronary
interventions, management of left main disease, bifurcations,
chronic total occlusions, and new approaches to
treating these challenging areas. For structural heart disease,
we will have a full program on mitral valve repair, as well as
aortic valve therapies/implantations with devices.
There will also be an interventional oncology symposium, which has been included in the ISET program for the last 2 years. Interventional oncology is a foreign land, and we have to learn everything. A lot of our general endovascular techniques apply to this new area of interest because the delivery of drug therapy is part of endovascular therapy as well.
What further exploration do you think is needed in
regard to structural heart repair?
There has been an explosion of new devices for valve
therapy, beginning with the first percutaneous implants
in the pulmonary valve in children and then Cribier
with the first implant in the aortic valve. Now, we are
refining percutaneous mitral valve repair. Industry is
also developing devices for the tricuspid valve, which is
a source of a significant amount of disease. The entire
field of percutaneous valve therapy is going to be a significant
area of growth in interventional procedures in
the near future.
What do you consider to be the most rewarding part of
your work? Which procedures do you most enjoy performing?
I enjoy the challenge of difficult cases. For example,
chronic total occlusions require a lot of patience and
preparation. Expertise is achieved by solid preparation
and striving to master both new techniques and the full
array of complementary equipment (ie, wires and
catheters). These cases bring great reward because
these patients truly benefit from the procedures.
In the structural arena, performing percutaneous mitral valve repair is the most rewarding of all the interventional procedures that I do. Some of these are highrisk patients who have no option whatsoever because of the nature of the mitral valve—and the same applies to the aortic valve; interventionists always believed that this area could not be tackled. We see these patients who are very high risk, who have a predicted surgical mortality rate of 18%, and we are able to improve their condition over 24 hours from New York Heart Association class 4 (severe) to class 1 or 2 (mild/moderate), which is really incredible.
What hobbies or interests do you engage in during
your free time?
I love golf. I have been playing golf since I was a kid. I'm
not a good golfer by any means, but I enjoy it very much. I
go out early in the morning and spend 3 or 4 hours outside
just enjoying nature. I'm the first one out there. This
way, I have the rest of the day to spend with my family.
I also really enjoy learning about art and history. I am an avid reader and traveler; I believe that the practice of medicine requires technical expertise that is grounded in a broad humanistic knowledge. My grandfather (who was a physician and writer) and my father (a cardiologist) always said, “Physicians who only know medicine do not know even medicine.” Hopefully, I have made this bit of wisdom part of my life in a positive way.
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