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Interventional Heart Failure
A new clinical subspecialty emerges.
By Navin K. Kapur, MD, FSCAI, FACC
From Door-to-Balloon to Door-to-Unload Time
An emerging view on the management of STEMI complicated by cardiogenic shock.
By Navin K. Kapur, MD
Why Do We Need the Door-to-Unload Trial for Anterior STEMI?
An opportunity to improve outcomes for millions of STEMI patients worldwide.
By Navin K. Kapur, MD, FAHA, FACC, FSCAI
First Patient Enrolled in Abiomed's STEMI DTU Feasibility Study
May 5, 2017—Abiomed, Inc. announced the enrollment of the first patient in the prospective feasibility study of ST-segment elevation myocardial infarction (STEMI) door to unloading (DTU) with the company's Impella CP system in acute myocardial infarction.
Delayed Reperfusion With Left-Ventricular Support Evaluated in STEMI DTU
March 28, 2026—The STEMI DTU randomized trial of ST-elevation myocardial infarction and door-to-unloading time showed that delayed reperfusion with left-ventricular (LV) support to reduce heart damage resulted in no significant difference compared with standard immediate percutaneous coronary intervention (PCI) in patients with heart attacks at risk for a large amount of heart damage.
Study Evaluates LV Unloading with Abiomed Impella for 30 Minutes Before PCI in STEMI Patients
September 17, 2022—Abiomed announced results of a new per-protocol analysis of data from the ST-segment Elevation Myocardial Infarction Door-To-Unload (STEMI DTU) pilot trial.
FDA Approves Abiomed’s RECOVER IV RCT With Exception From Informed Consent
September 16, 2022—Abiomed announced two FDA approvals related to clinical research of the company’s Impella heart pump in acute myocardial infarction (AMI) cardiogenic shock patients.
PCI in Practice and Update on Mechanical Circulatory Support
By Christopher Cook, BSc, MBBS, MRCP, PhD, and M. Chadi Alraies, MD
THV Expansion
By Ted E. Feldman, MD, MSCAI, FACC, FESC
The Radial Shift
By Ted E. Feldman, MD, FESC, FACC, FSCAI