SyMap Medical Closes Financing to Support Clinical Trials

December 7, 2021—SyMap Medical announced the closing of a financing round of approximately $100 million. SyMap is a China-based company focused on developing device-based therapies for cardiovascular and pulmonary diseases including hypertension, heart failure, arrhythmia, asthma, and early-stage lung cancer.

According to the company, the funds will be used to accelerate global clinical trials for SyMap’s renal denervation (RDN) products, facilitate the next generation of renal mapping/selective RDN systems and products in interventional pulmonary space, and codevelop technologies with partners in the United States and Israel.

The financing round was led by Primavera Capital and VMS Group, with the participation of existing investors Simiao Equity Investment and Sequoia Capital China. CEC Capital served as the exclusive financial advisor for this transaction.

SyMap noted it is conducting two pivotal trials in China:

• SMART, the Sympathetic Mapping/Ablation of Renal Nerves Trial, is evaluating the company’s SyMapCath I catheter/Sympioneer S1 RF system for the treatment of uncontrolled hypertension. The system is intended to map renal nerves for selective renal sympathetic denervation and to provide feedback for physicians before, during, and after the procedure.
• BATA, the Bronchial Ablation for Treatment of Asthma study, is assessing the efficacy and safety of the Elation system to treat severe asthma via bronchial radiofrequency ablations.

Both studies are executed by leading clinical investigators and are guided by international experts who serve on the company’s Scientific Advisory Boards. Both systems have been granted “Green Channel Device” status by China’s regulatory agency, advised SyMap Medical.

SyMap is headquartered in BioBay in Suzhou, China. The company was cofounded by Jie Wang, MD, and Mr. Kewen Jin. Dr. Wang is a faculty member of the College of Physicians & Surgeons of Columbia University in New York, New York. He is professor at the Jiangsu Province Hospital and is the former Dean of Nanjing University's medical school in Nanjing, China.