SCCT/SCAI Consensus Statement Standardizes Use of CT-Derived FFR

June 4, 2026—The Society of Cardiovascular Computed Tomography (SCCT) announced that, in collaboration with the Society for Cardiovascular Angiography and Interventions (SCAI), it has released an expert consensus document on the use of coronary CT angiography (CCTA)-derived fractional flow reserve (FFR-CT) for assessing coronary artery disease. The document was endorsed by the American College of Cardiology.

According to the SCCT press release, the document provides evidence-based guidelines for the acquisition, interpretation, and reporting of FFR-CT, emphasizing its role in improving diagnostic accuracy, guiding clinical management, and reducing unnecessary invasive procedures. Additionally, the document discusses clinical applications for FFR-CT, including stable chest pain, multivessel disease, acute chest pain and special circumstances; prognostic value; reporting; and future directions.

Jonathan Weir-McCall, MBChB, and Ronak Rajani, MD, are the writing group cochairs for the document, which is available online in the Journal of Cardiovascular Computed Tomography.

“It was felt that the literature had reached a state of maturity where we could start to provide guidelines to the wider community that were based on what the evidence suggests we should do,” commented Dr. Weir-McCall in the SCCT press release.

As summarized in the press release, Dr. Weir-McCall explained that FFR-CT was also becoming a more commonly used tool in community hospitals and is “reaching out across the globe,” creating this need to standardize practice and provide a framework for the optimal acquisition of CCTA for the use of FFR-CT, appropriate selection of cases for FFR-CT usage, interpretation, and reporting of outputs.

The SCCT press release outlined the cochairs’ top takeaways from the document:

1. High-quality CCTA imaging is essential for accurate FFR-CT computation. The use of nitroglycerin and heart rate control also improve diagnostic accuracy, and that motion artifacts and calcification can impact FFR-CT reliability.
2. The biggest role for FFR-CT is in patients with stable chest pain and assessing intermediate stenosis to guide revascularization decisions.
3. FFR-CT values should be integrated into CCTA reports, with stenosis-specific values measured 2 cm distal to the lesion.